PostgraduateFull-time

Novel functions of the epigenetic cancer driver KMT2D

Aston UniversityUnited Kingdom
Level
Postgraduate
Mode
Full-time
Subject
Biological Sciences
Location
United Kingdom
Next intake
OCT 2026

Overview

KMT2D, previously also known as MLL2 in humans, is a histone 3 lysine 4 (H3K4) methyltransferase. It has attracted attention as it is within the top 10 most mutated genes in cancer genomes, as well as the main reason behind the congenital disorder Kabuki syndrome. Importantly, in contrast to other cancer genes, the functions of KMT2D have not been clearly established yet. It is believed that KMT2D works through methylating H3K4 in chromatin, a mark of active transcription, and facilitating enhancer mediated transcriptional activation.

English language requirements

IELTS6.5 overall

IELTS 6.5 overall (component minima vary by programme; see university English-language requirements)

Start dates

October 2026

Campus

  • Birmingham, United Kingdom
East MidlandsEast of EnglandLondonNorth EastNorth WestNorthern IrelandScotlandSouth EastSouth WestWalesWest MidlandsYorkshire and the HumberAston University

Where you will study

Birmingham, West Midlands, United Kingdom

Study in BirminghamWest Midlands

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